I roto i nga kiore, ka taea e te momi me te koroheketanga te whakararu i te koiora o te nicotinamide adenine dinucleotide (NAD +), e arai atu ana ki te mate o te mate. Te waatea o te nicotinamide mononucleotide(NMN)ko te reiti-tauwehe here i roto i te whakangote NAD+ biosynthesis.
I te Paenga-whawha 22, 2021, i whakaputaina e te roopu a Samuel Klein o te Whare Wananga o Washington i Amerika tetahi pepa rangahau e kiia ana "Nicotinamide mononucleotide e whakanui ana i te tairongo o te insulin i roto i nga wahine prediabetic" i roto i te Science Online. I whakahaerehia e te rangahau he 10-wiki matapōkeretia, placebo-whakahaere, He whakamatautau matapo-rua hei arotake i te paanga o te taapiringa NMN ki te mahi metabolic o nga wahine e taumaha ana, e momona ana ranei i muri i te menopause.
Whai muri i te taapiri me te NMN, ka aromatawaihia te whakamahi hukahuka whakaihiihi i te insulin ma te whakamahi i te rawhi hyperinsulinemic{1}}hyperglycemic. Ko te tohu o te insulin ira uaua (phosphorylation o AKT me te mTOR) kua piki ake, engari kaore i rereke i muri i te maimoatanga placebo. Ko te taapiri o te NMN-e whakarite ana i te whakaputanga o te pereti{5}}i takea mai i te kaikawe tauwehe tupu me etahi atu ira e pa ana ki te whakahou i nga uaua. Ko enei hua e tohu ana ka taea e te NMN te whakanui ake i te uaua o te insulin, te tohu o te insulin me te whakahou i nga wahine e pa ana ki te taumaha, momomo ranei i mua i te-wahine mate huka.
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